- tracked the real cost
- read the fine print
Rx.com review
Semaglutide $175/mo with no commitment; the advertised $146 is $875 prepaid for six months. Nothing renews on its own, which is rare.
- HSA / FSA-eligible
- Read every disclosure
- No insurance needed
Rx.com at a glance
- Semaglutide
- $175/mo
- Tirzepatide
- $285/mo
- Coverage
- 49 states — all except Alaska, per its own FAQ
- Brand-name
- Compounded only
How I scored Rx.com
Every factor here comes from Rx.com's own pricing, its disclosures and the signup I walked, and the six add up to the 80/100 Mom-Tested Score on the same weighted six-factor method I use on every provider — never nudged by whether a provider pays us.
A manageable start, with some friction worth planning around.
Fair, once you've read past the plan structure or an intro rate.
Scores low on choice — the medication menu is narrower here.
Wide coverage, but worth confirming your own state before you commit.
Standard support — enough to stay on track, not high-touch.
Leaving is about as easy as joining.
How I verified this review
- Last verified
- September 2026
- Confidence
- high
- Primary source
- rx.com
$175 and $285 month to month, flat at every dose, with the visit, syringes and cold shipping inside. The advertised $146 is the six-month prepay, $875 at once. Nothing renews on its own — they check in before every refill. 49 states, not 50; Alaska is out.
Pricing
Prices re-verified
| Medication | Monthly | Plan |
|---|---|---|
| Compounded semaglutide | $175 | Any dose, month to monthThe one-month plan, $175 in a single payment — what you pay if you don't prepay anything. |
| Compounded semaglutide | $165 | Any dose, 3-month plan$495 in one payment, not a monthly rate. |
| Compounded semaglutide | $146 | Any dose, 6-month plan⛔ THIS IS THE ADVERTISED $146 — $875 up front for six months. The homepage badges it an "Exclusive Lifetime Offer" without saying on the same line that you prepay the half-year. |
| Compounded tirzepatide | $285 | Any dose, month to monthThe one-month plan, $285 in a single payment. |
| Compounded tirzepatide | $259 | Any dose, 6-month plan$1,550 in one payment — where the $259 in comparisons comes from. The 3-month plan is $265 ($795). |
HSA and FSA usually work for this — worth checking your own plan. The prices here are what Rx.com's public disclosures showed at last review, and they change often; confirm the current number on Rx.com's own site.
What I like
- The entire price table is published before any intake
- Flat pricing at every dose, with the milligram ranges published
- Nothing renews automatically — they confirm with you before every refill
- Visit, syringes, cold shipping and unlimited messaging are inside the price
- It names the state it excludes instead of promising all fifty
The caveats
- The advertised $146 is the six-month plan, $875 in one payment
- The homepage badge promises 50 states while the program FAQ says 49
- Alaska is excluded, and some states add a required video visit
- Shipped medication can't be returned
- Compounded only — no brand-name path
- Nothing about how long to wait postpartum, or about nursing beyond the exclusion
What I actually think of Rx.com
Semaglutide $175/mo with no commitment; the advertised $146 is $875 prepaid for six months. Nothing renews on its own, which is rare. It runs about $175/month, and it's flat at every dose.
I look at Rx.com the way moms actually have to — not just the real monthly number, but nursing and pregnancy timing and canceling without a fight. That's the stuff a generic weight-loss review skips right over.
What Rx.com really costs
- Compounded semaglutide — Any dose, month to month: $175/mo
- Compounded semaglutide — Any dose, 3-month plan: $165/mo
- Compounded semaglutide — Any dose, 6-month plan: $146/mo
- Compounded tirzepatide — Any dose, month to month: $285/mo
- Compounded tirzepatide — Any dose, 6-month plan: $259/mo
That's about in line with the ~$179/month middle of my shortlist.
Which meds Rx.com prescribes
Rx.com prescribes semaglutide and tirzepatide — the two with the strongest published weight-loss numbers, and having both on one account genuinely matters if insulin resistance is in the mix (which it often is with PCOS or after gestational diabetes), because that's when tirzepatide tends to be the better fit. These are compounded from a licensed pharmacy — that's why the price stays down — but compounded GLP-1s aren't FDA-approved finished products the way Wegovy and Zepbound are, and it's worth knowing that going in.
Who Rx.com is — and isn't — for
A good fit if…
- money is the actual barrier and you want a low, predictable number you can plan around.
- you might need to move between semaglutide and tirzepatide as your body and hormones shift.
Look elsewhere if…
- you specifically want an FDA-approved brand pen with its own pregnancy and lactation labeling.
- you'd rather a prescriber actually talk through nursing and pregnancy timing with you — that's what my #1 pick, CoreAge Rx, is built to do.
Can you trust it?
I'm confident in the public facts on Rx.com — pricing, pharmacies, and the clinical network all checked out when I last looked. With any compounded GLP-1, the most useful thing you can do is confirm which licensed pharmacy fills it and what's actually in the formulation — I explain how I weigh oversight in the scoring method.
A standing caveat, because I'm a mom writing this and not your doctor: GLP-1 meds aren't established as safe during pregnancy or breastfeeding, and every label advises against it. Nothing here changes that — plan the timing with your own clinician.
So, would I use it?
Rx.com is a reasonable option — weigh it against the picks below on nursing and pregnancy timing and canceling without a fight. For most moms, CoreAge Rx is still the stronger all-round fit — and you can see them side by side in this head-to-head.
The bottom line for moms
Best for: A mom who wants the whole price table before handing over a detail, and who'd rather never be auto-charged than chase the lowest number.
If Rx.com isn't the one
Providers I have a referral relationship with, ordered by Mom-Tested Score — highest first. A fee never moves a score, but it does decide who shows up in this box, so it isn't everyone: my full ranking has every provider, paid or not.
- Visit CoreAge RxMom-Tested Score94/100ACoreAge RxMy #1 pick
The one I'd point a friend to first: I finished the intake in a single nap, the price on screen was the price I'd actually pay, and both semaglutide and tirzepatide were right there on one account.
- Visit Pallas HealthMom-Tested Score86/100B+
Pallas is one of the few places that will sell you either the cheap compounded route or the real brand-name pen without making you pick a provider first — compounded semaglutide works out to about $199 a month and tirzepatide about $299, while actual Zepbound, Ozempic, Wegovy and Mounjaro sit alongside them at cash-pay prices from $1,069. The price genuinely doesn't climb as you titrate, Pallas says so plainly on its own site, and the clinician, dose adjustments, check-ins and messaging are all inside that one number with no membership fee stacked on top. Two clinicians are named and both check out in the federal NPI registry, the LegitScript badge it displays is a real one, and it publishes an actual refund policy — full refund if a clinician turns you down, and a $5 processing fee if you cancel a qualifying payment — which is more paperwork than most of this market bothers with. The two things to know before you commit: it bills every 12 weeks in $597 and $897 chunks rather than monthly, and it never names its compounding pharmacy.
- Visit Trimi HealthMom-Tested Score85/100B
The price-first pick: some of the lowest flat, all-inclusive pricing I found, in all 50 states — great if the monthly number is your whole decision and you read the annual-prepay fine print before you sign.
Keep comparing Rx.com
Head-to-head & alternatives
Rx.com, answered
- Is it really $146 a month?
- Only if you prepay half a year. The $146 is the six-month plan, billed as $875 in one go. Month to month, compounded semaglutide is $175 and you can stop whenever. The advertised figure is real — it's just an $875 decision, not a monthly one, and worth seeing that way before you click.
- Will it charge me automatically every month?
- No, and it's unusually plain about it. Its own page says the plan doesn't renew automatically and that nothing ships or is charged until you confirm with the care team before each refill. Canceling costs nothing. The only thing you can't undo is medication that's already shipped.
- Does the price climb as my dose does?
- No. Same figure from 0.25 to 2.4 mg of semaglutide and from 2.5 to 15 mg of tirzepatide, with the ranges published rather than implied. That matters most in the first months, when your dose almost certainly climbs and plenty of programs let the bill climb with it.
- Is it a video visit or a form?
- A form, mostly. It's a written questionnaire and a photo ID, with a licensed provider reviewing it — usually within 24 hours. Its own FAQ adds that some states require a short video visit, handled during intake, so which one you get depends on where you live.
Pricing, states and verification reflect Rx.com's public disclosures at last review; the Mom-Tested Score is one mom's editorial judgment per the published method. This is background reading, not medical advice — GLP-1 medications are not established as safe in pregnancy or breastfeeding. See my medical disclaimer and how I'm funded.