- walked the public signup
- tracked the real cost
- read the fine print
Open Water Rx review
A clean, all-inclusive flat price once you get past the promo codes — $249 semaglutide, $339 tirzepatide, plus a real oral tablet option at $279 — though a genuine price conflict I found across its own pages needed resolving before I'd trust the number.
then $249/mo ongoing
- HSA / FSA-eligible
- Walked the public signup
- No insurance needed
Open Water Rx at a glance
- Semaglutide
- $249/mo
- Tirzepatide
- $339/mo
- Coverage
- All 50 states (as advertised)
- Brand-name
- Compounded only
How I scored Open Water Rx
Every factor here comes from Open Water Rx's own pricing, its disclosures and the signup I walked, and the six add up to the 72/100 Mom-Tested Score on the same weighted six-factor method I use on every provider — never nudged by whether a provider pays us.
Scores low here: getting started asks more of your week than most.
Scores low: pinning down the real ongoing number takes work.
Scores high on medication choice — the options that matter are covered.
Wide coverage, but worth confirming your own state before you commit.
Support is the weakest part of this provider's score.
Exit terms are the weak point: lock-in, notice periods, or a cancellation you have to chase.
How I verified this review
- Last verified
- August 2026
- Confidence
- medium
- Primary source
- openwaterrx.com/pricing
$249 and $339, with an oral tablet at $279 if you'd rather skip needles. The $159 and $219 you'll see elsewhere on the site are promo-code prices, not the standard rate. The all-fifty-states claim is the site's own.
What to expect when you sign up
I walked Open Water Rx's public signup funnel (August 2026) — a first-hand look at the flow. I don't create accounts, enter medical info, or check out, so this is what any visitor sees, not a patient outcome.
- 1The signup call to action leaves openwaterrx.com for openwaterrx.l.openloop.ai, a separate host
- 2The intake responded HTTP 200 when checked on 2026-08-21
- 3Walked to the intake entry only. No personal information was submitted, so nothing past the entry screen is asserted here
What I noticed
- The intake runs on OpenLoop rather than on the provider's own software
- A monthly price is visible on the public homepage before any intake — you do not have to hand over information to see a number
- Intake is hosted on openwaterrx.l.openloop.ai, so the company you fill the form in with is not the domain you started on
Pricing
Prices re-verified
| Medication | Monthly | Plan |
|---|---|---|
| Compounded semaglutide | $159 → $249 | Weekly injection (flat)A SEMASUMMER promo code shows $159 elsewhere on the site; $249/mo is the standing price stated plainly on Open Water Rx's own /pricing page. |
| Compounded tirzepatide | $219 → $339 | Weekly injection (flat)A FOUNDER promo code shows $219 elsewhere on the site; $339/mo is the standing price on the /pricing page. |
| Oral semaglutide | $279 | Daily tabletA real, named oral semaglutide tablet — no injections. |
HSA and FSA usually work for this — worth checking your own plan. The prices here are what Open Water Rx's public disclosures showed at last review, and they change often; confirm the current number on Open Water Rx's own site.
What I like
- A real, named oral semaglutide tablet ($279/mo) — most budget compounders only offer the shot
- One flat, all-inclusive price with no separate consult fee, per its own FAQ
- Advertises coverage in all 50 states
- The standing $249/$339 rates are stated plainly, in one place, on its own /pricing page — resolving a price conflict an earlier check had flagged
The caveats
- The $159/$219 numbers you'll see elsewhere on the site are promo-code prices (SEMASUMMER/FOUNDER), not the standing $249/$339 rate
- Some states require a live video consultation before treatment, per its own hero copy — confirm yours before assuming a nap-length signup
- The 'all 50 states' claim is advertised, not independently checked state by state
- No named compounding pharmacy or medical director published
What I actually think of Open Water Rx
A clean, all-inclusive flat price once you get past the promo codes — $249 semaglutide, $339 tirzepatide, plus a real oral tablet option at $279 — though a genuine price conflict I found across its own pages needed resolving before I'd trust the number. The number they lead with is $159, but the price that sticks is closer to $249/month — so read the headline as a first-month offer, not the real monthly number.
I look at Open Water Rx the way moms actually have to — not just the real monthly number, but nursing and pregnancy timing and canceling without a fight. That's the stuff a generic weight-loss review skips right over.
What Open Water Rx really costs
- Compounded semaglutide — Weekly injection (flat): $159 to start, then $249/mo
- Compounded tirzepatide — Weekly injection (flat): $219 to start, then $339/mo
- Oral semaglutide — Daily tablet: $279/mo
For context, the typical ongoing price across my shortlist is around $179/month, so Open Water Rx sits at the pricey end.
Which meds Open Water Rx prescribes
Open Water Rx prescribes semaglutide and tirzepatide — the two with the strongest published weight-loss numbers, and having both on one account genuinely matters if insulin resistance is in the mix (which it often is with PCOS or after gestational diabetes), because that's when tirzepatide tends to be the better fit. These are compounded from a licensed pharmacy — that's why the price stays down — but compounded GLP-1s aren't FDA-approved finished products the way Wegovy and Zepbound are, and it's worth knowing that going in.
There's a needle-free sublingual option too, which is a relief if injections are the thing stopping you — just set expectations honestly: the under-the-tongue versions are far less studied than the shots the trials actually used.
Who Open Water Rx is — and isn't — for
A good fit if…
- you might need to move between semaglutide and tirzepatide as your body and hormones shift.
- staying covered no matter where you are matters — a move for family shouldn't blow up your care.
Look elsewhere if…
- you specifically want an FDA-approved brand pen with its own pregnancy and lactation labeling.
- you'd rather a prescriber actually talk through nursing and pregnancy timing with you — that's what my #1 pick, CoreAge Rx, is built to do.
Can you trust it?
My confidence is middling — the core facts hold up, but some details (per-state availability, how the program really runs) aren't fully public. With any compounded GLP-1, the most useful thing you can do is confirm which licensed pharmacy fills it and what's actually in the formulation — I explain how I weigh oversight in the scoring method.
One line that's true of every provider on this site: no GLP-1 is established as safe in pregnancy or while breastfeeding, and the labels say don't. This is me reviewing a commercial signup, not giving you a green light — the timing call is yours and your clinician's.
So, would I use it?
Open Water Rx is a reasonable option — weigh it against the picks below on nursing and pregnancy timing and canceling without a fight. For most moms, CoreAge Rx is still the stronger all-round fit — and you can see them side by side in this head-to-head.
The bottom line for moms
Best for: Moms who want an oral tablet option alongside the injections, are comfortable with an all-50-states claim that's advertised rather than independently checked, and don't mind that a live video visit is required in some states.
If Open Water Rx isn't the one
Providers I have a referral relationship with, ordered by Mom-Tested Score — highest first. A fee never moves a score, but it does decide who shows up in this box, so it isn't everyone: my full ranking has every provider, paid or not.
- Visit CoreAge RxMom-Tested Score94/100ACoreAge RxMy #1 pick
The one I'd point a friend to first: I finished the intake in a single nap, the price on screen was the price I'd actually pay, and both semaglutide and tirzepatide were right there on one account.
- Visit Pallas HealthMom-Tested Score86/100B+
Pallas is one of the few places that will sell you either the cheap compounded route or the real brand-name pen without making you pick a provider first — compounded semaglutide works out to about $199 a month and tirzepatide about $299, while actual Zepbound, Ozempic, Wegovy and Mounjaro sit alongside them at cash-pay prices from $1,069. The price genuinely doesn't climb as you titrate, Pallas says so plainly on its own site, and the clinician, dose adjustments, check-ins and messaging are all inside that one number with no membership fee stacked on top. Two clinicians are named and both check out in the federal NPI registry, the LegitScript badge it displays is a real one, and it publishes an actual refund policy — full refund if a clinician turns you down, and a $5 processing fee if you cancel a qualifying payment — which is more paperwork than most of this market bothers with. The two things to know before you commit: it bills every 12 weeks in $597 and $897 chunks rather than monthly, and it never names its compounding pharmacy.
- Visit Trimi HealthMom-Tested Score85/100B
The price-first pick: some of the lowest flat, all-inclusive pricing I found, in all 50 states — great if the monthly number is your whole decision and you read the annual-prepay fine print before you sign.
Keep comparing Open Water Rx
Head-to-head & alternatives
Open Water Rx, answered
- How much does Open Water Rx cost?
- As I last checked, Open Water Rx's pricing starts around $249/month ($249/mo semaglutide, $339/mo tirzepatide). Confirm the current, all-in number on Open Water Rx's own site before you commit — these move.
- Is Open Water Rx okay to use while I'm breastfeeding?
- No — and that's true of every GLP-1, compounded or brand: none is established as safe in pregnancy or breastfeeding, and the labels say don't. Open Water Rx is no exception. Plan any GLP-1 for after weaning and talk the timing through with your own clinician. I'm a mom, not a doctor.
- Does Open Water Rx have both semaglutide and tirzepatide?
- Yes — Open Water Rx offers both. Tirzepatide's dual GIP/GLP-1 action is often the one clinicians reach for when insulin resistance drives weight, which matters if you've got PCOS or a history of gestational diabetes.
- Where does Open Water Rx land on your list?
- Open Water Rx scores 72/100 on the Mom-Tested Score (ranked #51), which weights the six things that actually matter when you're doing this around kids. My #1 pick, CoreAge Rx, leads the list — worth seeing how they stack up.
Pricing, states and verification reflect Open Water Rx's public disclosures at last review; the Mom-Tested Score is one mom's editorial judgment per the published method. This is background reading, not medical advice — GLP-1 medications are not established as safe in pregnancy or breastfeeding. See my medical disclaimer and how I'm funded.