Matched on what Direct Meds offers: medications, brand-name access, the video visit, an oral option, price and where it serves. Each one links to our full review.
Semaglutide from $249/mo · Tirzepatide from $299/mo
Semaglutide shots at $249 a month and tirzepatide at $299 after a $99 first month, with a sublingual tablet for either if you'd rather skip the needle — but the FDA issued its parent entity, Lean Rx, Inc., a warning letter on 02/20/2026 (ref. 717989) for mislabeling itself as the compounder on its own product images and for marketing language implying its compounded products share FDA-approved status with Mounjaro and Zepbound, which they don't.
Why it's here: the same medications, compounded medication and no video visit.
- SkinnyRx lists semaglutide at $249 a month; we couldn't find a recurring semaglutide price for Direct Meds.
- SkinnyRx lists tirzepatide at $299 a month; we couldn't find a recurring tirzepatide price for Direct Meds.
- Neither SkinnyRx nor Direct Meds requires a live video visit to get started.
- SkinnyRx has received an FDA warning letter of its own; our review covers what it says.
Semaglutide from $129/mo · Tirzepatide from $149/mo
Strut advertises injectable semaglutide at $129 a month and tirzepatide from $149. Its oral semaglutide pages disagree on price.
Why it's here: the same medications, compounded medication and no video visit.
- Strut Health lists semaglutide at $129 a month; we couldn't find a recurring semaglutide price for Direct Meds.
- Strut Health lists tirzepatide at $149 a month; we couldn't find a recurring tirzepatide price for Direct Meds.
- Neither Strut Health nor Direct Meds requires a live video visit to get started.
- Strut Health has received an FDA warning letter of its own; our review covers what it says.
Semaglutide from $299/mo · Tirzepatide from $399/mo
It just tells you the price and then charges it — $299 or $399, injection or tablet, no first-month bait — and it puts its doctors' names on a public page.
Why it's here: the same medications, compounded medication and no video visit.
- Willow lists semaglutide at $299 a month; we couldn't find a recurring semaglutide price for Direct Meds.
- Willow lists tirzepatide at $399 a month; we couldn't find a recurring tirzepatide price for Direct Meds.
- Neither Willow nor Direct Meds requires a live video visit to get started.
Semaglutide from $199/mo · Tirzepatide from $249/mo
Monthly plans are $199 for semaglutide and $249 for tirzepatide. Lower advertised rates require paying for three months upfront: $299 or $447 total.
Why it's here: the same medications, compounded medication and no video visit.
- Ascend Vitality lists semaglutide at $199 a month; we couldn't find a recurring semaglutide price for Direct Meds.
- Ascend Vitality lists tirzepatide at $249 a month; we couldn't find a recurring tirzepatide price for Direct Meds.
- Neither Ascend Vitality nor Direct Meds requires a live video visit to get started.
Semaglutide from $195/4 wks · Tirzepatide from $280/4 wks
Rixa shows every level, every dose and every price. Semaglutide goes $195, $225, $265, $290, $310.
Why it's here: the same medications, compounded medication and no video visit.
- Rixa Health lists semaglutide at $195 per 4 weeks; we couldn't find a recurring semaglutide price for Direct Meds.
- Rixa Health lists tirzepatide at $280 per 4 weeks; we couldn't find a recurring tirzepatide price for Direct Meds.
- Neither Rixa Health nor Direct Meds requires a live video visit to get started.
Semaglutide from $179/mo · Tirzepatide from $239/mo
Three formats with a full table, semaglutide $179/mo — but the guarantee has no written conditions and no states are listed.
Why it's here: the same medications, compounded medication and no video visit.
- Edessa lists semaglutide at $179 a month; we couldn't find a recurring semaglutide price for Direct Meds.
- Edessa lists tirzepatide at $239 a month; we couldn't find a recurring tirzepatide price for Direct Meds.
- Neither Edessa nor Direct Meds requires a live video visit to get started.
- Edessa doesn't publish a full state list; Direct Meds lists a narrower service area.