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Alternatives · compared for moms

Alternatives to Direct Meds

Injection or sublingual, both molecules — but with two warnings attached: a 2025 FDA warning letter, and a semaglutide injection sold as a 90-day supply billed monthly, so check the supply length before you pay.

Read our full Direct Meds review

Direct Meds at a glance

  • Direct Meds offers compounded semaglutide and tirzepatide.
  • Direct Meds doesn't list a plain recurring price: its lowest figure, $249 a month for semaglutide, depends on a plan term or a required membership, so check the full cost before you pay.
  • Direct Meds lets you start without a live video visit.
  • Where it serves: Most states (not MS or LA).

Why you might look past Direct Meds

  • September 2025 FDA warning letter for marketing compounded GLP-1s as equivalent to FDA-approved drugs
  • The semaglutide injection is sold as a 90-day supply shipped at once and billed monthly — check the supply length before you pay
  • Renews every 30 days until you turn off auto-refill in your account at least 48 hours before the next charge

Who Direct Meds suits

A mom who wants a sublingual option and has read the FDA warning and the billing terms first — and who will check the supply length at checkout.

Our featured partner

Grade A

CoreAge Rx

A featured partner advertising compounded semaglutide at $79 and tirzepatide at $129 a month, with the same price at every listed dose, supplies and shipping included.

Semaglutide from $79/mo · Tirzepatide from $129/mo

Providers that work most like Direct Meds

Matched on what Direct Meds offers: medications, brand-name access, the video visit, an oral option, price and where it serves. Each one links to our full review.

SkinnyRx

Partner

Semaglutide from $249/mo · Tirzepatide from $299/mo

Semaglutide shots at $249 a month and tirzepatide at $299 after a $99 first month, with a sublingual tablet for either if you'd rather skip the needle — but the FDA issued its parent entity, Lean Rx, Inc., a warning letter on 02/20/2026 (ref. 717989) for mislabeling itself as the compounder on its own product images and for marketing language implying its compounded products share FDA-approved status with Mounjaro and Zepbound, which they don't.

Why it's here: the same medications, compounded medication and no video visit.

  • SkinnyRx lists semaglutide at $249 a month; we couldn't find a recurring semaglutide price for Direct Meds.
  • SkinnyRx lists tirzepatide at $299 a month; we couldn't find a recurring tirzepatide price for Direct Meds.
  • Neither SkinnyRx nor Direct Meds requires a live video visit to get started.
  • SkinnyRx has received an FDA warning letter of its own; our review covers what it says.

Semaglutide from $129/mo · Tirzepatide from $149/mo

Strut advertises injectable semaglutide at $129 a month and tirzepatide from $149. Its oral semaglutide pages disagree on price.

Why it's here: the same medications, compounded medication and no video visit.

  • Strut Health lists semaglutide at $129 a month; we couldn't find a recurring semaglutide price for Direct Meds.
  • Strut Health lists tirzepatide at $149 a month; we couldn't find a recurring tirzepatide price for Direct Meds.
  • Neither Strut Health nor Direct Meds requires a live video visit to get started.
  • Strut Health has received an FDA warning letter of its own; our review covers what it says.

Willow

Partner

Semaglutide from $299/mo · Tirzepatide from $399/mo

It just tells you the price and then charges it — $299 or $399, injection or tablet, no first-month bait — and it puts its doctors' names on a public page.

Why it's here: the same medications, compounded medication and no video visit.

  • Willow lists semaglutide at $299 a month; we couldn't find a recurring semaglutide price for Direct Meds.
  • Willow lists tirzepatide at $399 a month; we couldn't find a recurring tirzepatide price for Direct Meds.
  • Neither Willow nor Direct Meds requires a live video visit to get started.

Semaglutide from $199/mo · Tirzepatide from $249/mo

Monthly plans are $199 for semaglutide and $249 for tirzepatide. Lower advertised rates require paying for three months upfront: $299 or $447 total.

Why it's here: the same medications, compounded medication and no video visit.

  • Ascend Vitality lists semaglutide at $199 a month; we couldn't find a recurring semaglutide price for Direct Meds.
  • Ascend Vitality lists tirzepatide at $249 a month; we couldn't find a recurring tirzepatide price for Direct Meds.
  • Neither Ascend Vitality nor Direct Meds requires a live video visit to get started.

Semaglutide from $195/4 wks · Tirzepatide from $280/4 wks

Rixa shows every level, every dose and every price. Semaglutide goes $195, $225, $265, $290, $310.

Why it's here: the same medications, compounded medication and no video visit.

  • Rixa Health lists semaglutide at $195 per 4 weeks; we couldn't find a recurring semaglutide price for Direct Meds.
  • Rixa Health lists tirzepatide at $280 per 4 weeks; we couldn't find a recurring tirzepatide price for Direct Meds.
  • Neither Rixa Health nor Direct Meds requires a live video visit to get started.

Semaglutide from $179/mo · Tirzepatide from $239/mo

Three formats with a full table, semaglutide $179/mo — but the guarantee has no written conditions and no states are listed.

Why it's here: the same medications, compounded medication and no video visit.

  • Edessa lists semaglutide at $179 a month; we couldn't find a recurring semaglutide price for Direct Meds.
  • Edessa lists tirzepatide at $239 a month; we couldn't find a recurring tirzepatide price for Direct Meds.
  • Neither Edessa nor Direct Meds requires a live video visit to get started.
  • Edessa doesn't publish a full state list; Direct Meds lists a narrower service area.

Some providers we list are partners, and we may be paid when you sign up through our links. That can affect which providers we feature. Prices are the providers' own published figures and change often. Scores are our editorial judgment per the methodology. Not medical advice; see our disclosure.

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